Tissue factor positive neutrophils bind to injured endothelial wall and initiate thrombus formation Running title: Neutrophils initiate thrombus formation in vivo
نویسندگان
چکیده
Aix Marseille Université, Campus Santé, 27 Boulevard Jean Moulin, Marseille, France. INSERM UMR-S1076, Faculty of Pharmacy, 27 Boulevard Jean Moulin, 13385 Marseille, France. Immune Disease Institute and Program in Cellular and Molecular Medicine, Children’s Hospital Boston; Department of Pediatrics, Harvard Medical School, 3 Blackfan circle, Boston, MA 02215, USA.INSERM UMR-911, 27 Boulevard Jean Moulin, 13385 Marseille, France.Division of Hematology/oncology, Department of Medicine, 917 Mary Ellen Jones Building, University of North Carolina, Chapel Hill, NC 27599, USA. Department of Molecular Medicine and Surgery and Center of Molecular Medicine, Karolinska Institute and University Hospital, 17176, Stockholm, Sweden.
منابع مشابه
Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation.
For a long time, blood coagulation and innate immunity have been viewed as interrelated responses. Recently, the presence of leukocytes at the sites of vessel injury has been described. Here we analyzed interaction of neutrophils, monocytes, and platelets in thrombus formation after a laser-induced injury in vivo. Neutrophils immediately adhered to injured vessels, preceding platelets, by bindi...
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